Developed to help fight breast cancer, Aromasin is one of the most powerful estrogen suppressing compounds
Exemestane
6-Methylenandrosta-1,4-diene-3,17-dione; 10,13-Dimethyl-6-methylidene-7,8,9,10,11,12,13,14,15,16-decahydrocyclopenta[a]phenanthrene-
| Molecular Formula | C20H24O2 | |
| Molecular Weight | 296.40 | |
| CAS Registry Number | 107868-30-4 |
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Developed to help fight breast cancer, Aromasin is one of the most powerful estrogen suppressing compounds available for body builders taking anabolic steroids. Additionally, it also raises testosterone in the body, which is a bonus for bodybuilders during post-cycle-therapy.
Aromasin (Exemestane): A Profile
Aromasin, the brand name for exemestane, is a powerful steroidal aromatase inhibitor (AI) primarily prescribed to treat hormone receptor-positive breast cancer in postmenopausal women. As part of hormone therapy, it is often used following initial treatment with medications like tamoxifen, especially in early or advanced breast cancer cases. Aromasin plays a critical role in reducing the risk of cancer recurrence and slowing the growth of estrogen-dependent tumors.
Exemestane works by irreversibly binding to and inactivating the aromatase enzyme, which converts androgens into estrogen. This “suicide inhibition” effectively lowers estrogen levels in the body, depriving estrogen-sensitive cancer cells of the fuel they need to grow and spread. The irreversible nature of Aromasin’s action distinguishes it from non-steroidal AIs, offering robust and lasting results.
Beyond its medical use, Aromasin is also popular in athletic and bodybuilding communities. It is used to combat estrogenic side effects caused by anabolic steroid use, such as gynecomastia (male breast tissue development) and water retention. By reducing estrogen levels, Aromasin helps maintain a leaner, more defined physique.
While Aromasin is effective, it is not without potential side effects. Common adverse effects include joint pain, hot flashes, fatigue, mild nausea, and sweating. Long-term use may reduce bone mineral density, so users are often advised to supplement with calcium and vitamin D.
As a versatile and effective aromatase inhibitor, Aromasin remains a trusted option for managing both estrogen-driven cancers and hormonal imbalances in performance contexts. Close monitoring and healthcare supervision are essential for its safe and effective use.
